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Cell lysate was then diluted with lysate buffer and divided into two aliquotsone treated with C1-27 (100 M) and the other treated with 1% DMSO

Transported by chylomicrons and very low-density lipoproteins, triglycerides are hydrolyzed by high lipase concentrations in the pancreatic capillaries, where they form a large amount of toxic free fatty acids that cause lipotoxicity in acute pancreatitis (186)

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Recruited originally to help improve laundry detergent enzymes to make clothes look brighter, Knudsen soon got drawn into a small team set up in 1990 by Ole Kirk, an organic chemist and physician, to discover new peptide candidates to treat type 2 diabetes (Molteni, Chen